天津科技大学生物工程学院欢迎您!
讲师


                李中媛,女,理学博士,天津科技大学生物学院助理研究员, 131”创新型人才工程第三层次人选,天津市科技特派员,天津市微生物学会员。主讲《微生物实验技术》和《制药工艺试验》课程。致力于肠道微生态调控、农产品质量安全和生物质能源高效利用的研究及相关功能产品的开发。已在Appl Environ Microbiol,FEBS Journal, Appl Microbiol Biotechnol,Bioresource Technol等期刊发表论文10余篇,其中以第一或通讯作者身份发表SCI论文8篇,JCR 2区5篇,TOP期刊3篇。申请国家专利5项,授权1项。累计到账经费90万元,培养研究生6人。

承担项目:
1、主持国家自然科学基金青年项目1项
2、主持国家重点研发计划“政府间国际科技创新合作”专项子课题1项
3、主持农业部饲料生物技术重点实验室开放课题1项
4、主持天津市高等学校科技发展基金计划项目1项
5、主持天津科技大学青年教师创新基金1项
6、主持天津科技大学新农村发展研究院开放课题基金1项

同时参与国家重点研发计1项,国家自然科学基金4项,天津市应用基础与前沿技术研究计划1项,“863”计划2项。

获奖情况:
1、天津科技大学生物工程学院第二届青年教师教学基本功竞赛二等奖
2、天津科技大学第十届青年教师教学基本功竞赛优秀奖
3、第四届环渤海微生物学术研讨会优秀论文奖
4、指导学生李琨、陆斌和牛天鸣获得天津科技大学2014年“酶好明天”泰达诺维信创新大赛校级三等奖
5、指导学生张扬获得生物工程学院“海河杯”生物科技创新竞赛一等奖
6、获得2013届“中国农业科学院优秀毕业生”称号
7、获得2013年研究生国家奖学金

已发表文章:
1.Hui Wang; Zhongyuan Li*(Corresponding authors); Huihui Liu; huang Li; Haiyan Qiu; Kun Li; Xuegang Luo; Yajian Song; Nan Wang; Hongpeng He; Hao Zhou; Wenjian Ma; Tongcun Zhang. Heterologous expression and characterization of a novel GH11 xylanase with excellent tolerance to alkali, aalt and ethanol from saline-alkali soil in Pichia pastoris. Protein Expression and Purification. 2017, Nov;139:71-77. 

2.Wang cuiqiong; Li Zhongyuan*(Corresponding authors); Wang Hui; Qiu  haiyan; Zhang minghui; Li shuang; Luo xuegang; Song yajian; Zhou hao; Ma wengjian; Zhang tongcun. Rapid biodegradation of aflatoxin B1 by metabolites of Fusarium sp. WCQ3361 with broad working temperature range and excellent thermostability. J Sci Food Agric. 2017, Mar;97(4):1342-1348. (JCR 2区)

3.Haiyan Qiu; Zhongyuan Li*(Corresponding authors); Hui Wang; Haiying Zhang; Shuang Li; Xuegang Luo; Yajian Song; Nan Wang; Hongpeng He; Hao Zhou; Wenjian Ma and Tongcun Zhang. Molecular and Biochemical Characterization of A Novel Cold Active and Metal ion-tolerant GH10 Xylanase from Frozen Soil. Biotechnology & Biotechnological Equipment. 2017, 31(5)955-963. 

4.Li Zhongyuan; Huang Huoqing; Zhao Heng*; Meng Kun; Zhao Junqi; Shi Pengjun; Yang Peilong; Luo Huiying; Wang Yaru; Yao Bin*. Genetic diversity and expression profiles of cysteine phytases in the sheep rumen during a feeding cycle. Letters in Applied Microbiology. 2014, 59(6):615–20.

5.Li Zhongyuan; Xue Xianli; Zhao Heng*; Yang Peilong; Luo Huiying; Zhao Junqi; Huang Huoqing; Yao Bin*. A C-Terminal Proline-Rich Sequence Simultaneously Broadens the Optimal Temperature and pH Ranges and Improves the Catalytic Efficiency of Glycosyl Hydrolase Family 10 Ruminal Xylanases. Applied and Environmental Microbiology. 2014, 80(11): 3426–3432. (JCR 2区top期刊)

6.Li Zhongyuan; Zhao Heng; Yang Peilong; Zhao Junqi; Huang Huoqing; Xue Xianli; Zhang Xinshang; Diao Qiyu; Yao Bin*. Comparative quantitative analysis of gene expression profiles of glycoside hydrolyses family 10 xylanase in the sheep rumen during a feeding cycle. Applied and Environmental Microbiology. 2013, 79(4):1212–1220.(JCR 2区top期刊)

7.Li Zhongyuan; Huang Huoqing; Yang Peilong; Yuan Tiezheng; Shi Pengjun; Zhao Junqi; Meng Kun; Yao Bin. The tandemly repeated domains of a β-propeller phytase act synergistically to increase catalytic efficiency. FEBS Journal. 2011,278(17):3032–3040.(JCR 2区)

8.Fu Dawei; Li Zhongyuan(Co-first author); Huang Huoqing; Yuan Tiezheng; Shi Pengjun; Luo Huiying; Meng Kun; Yang Peilong; Yao Bin. Catalytic efficiency of HAP phytases is determined by a key residue in close proximity to the active site. Applied Microbiology and Biotechnology. 2011, 90(4):1295–1302. (JCR 2区top期刊)

9.Zhao Junqi; Shi Pengjun; Li Zhongyuan; Yang Peilong; Luo Huiying; Bai Yingguo; Wang Yaru; Yao Bin. Two neutral thermostable cellulases from Phialophora sp. G5 act synergistically in the hydrolysis of filter paper. Bioresource Technology. 2012, 121:404–410.(JCR 1区top期刊)

10.Zhao Junqi; Shi Pengjun; Huang Huoqing; Li Zhongyuan; Yuan Tiezheng; Yang Peilong; Luo Huiying; Bai Yingguo; Yao Bin. A novel thermoacidophilic and thermostable endo-β-1,4-glucanase from Phialophora sp. G5: its thermostability influenced by a distinct β-sheet and the carbohydrate-binding module. Applied Microbiology and Biotechnology. 2012, 95(4):947–955.(JCR 2区top期刊)

专利:
1、李中媛, 张同存,仇海燕。一种低温木聚糖酶Xyn27及其基因和应用。中国发明专利,申请号201610012144.9
2、李中媛, 张同存, 张明慧,罗学刚,宋亚囝。一种低温的木糖苷/阿拉伯呋喃糖苷双功能酶AX543及其基因和应用。中国发明专利,申请号201510973509.9。
3、李中媛,张同存,王翠琼,罗学刚,宋亚囝。一株降解黄曲霉毒素B1的镰孢属菌及其应用。中国发明专利,申请号201610012423.4
4、李中媛,张同存,王翠琼,罗学刚,宋亚囝。一株降解黄曲霉毒素B1的枝顶孢属菌株及其应用。中国发明专利,申请号201610012424.9
5、姚斌,杨培龙,黄火清,李中媛,罗会颖,石鹏君,柏映国,孟昆和袁铁铮。 一种具有双结构域的低温中性植酸酶PhyH及其基因和应用. 中国发明专利,201110171735.7。

 

联系方式

办公地点:天津经济技术开发区第十三大街29号天津科技大学生物工程学院

邮政编码:300457

办公电话:022-60601104

传 真:022-60602298

Email:lizhongyuan@tust.edu.cn

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