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个人资料                                                           

籍贯:山东烟台  民族:汉  性别:  政治面貌:中共党员  出生年月:1983年6月

联系电话:18526306369, 15822909637邮箱yuaiqun@tust.edu.cn, yuaiqun12345@126.com

教育经历                                                             

2009年9月-2012年12月,南开大学生命科学学院,微生物学专业,理学博士。

20069-20096月,福建师范大学生命科学学院,微生物学专业, 理学硕士。

20029-20066月,山东师范大学生命科学学院,生物技术专业, 理学学士。

19999-20027月,山东省牟平第一中学

工作经历                                                             

*20169-至今                  天津科技大学                   内聘副教授

*201312-20165          新加坡国立大学                   博士后

*20133-201311           新加坡南洋理工大学              博士后

荣誉奖励                                                              

*2006年获得山东师范大学校级推荐就业优秀毕业生

*2011年获得南开大学光华奖学金三等奖

*2016年入选天津科技大学海河学者培育计划

*2016年入选天津市“131”创新型人才培养工程第三层次

科研成果                                                             

论文:

* Ai-Qun Yu, Nina Kurniasih Pratomo Juwono, Jee Loon Foo, Susanna Su Jan Leong, Matthew Wook Chang. Metabolic engineering of Saccharomyces cerevisiae for the overproduction of short branched-chain fatty acids. Metabolic Engineering, 2015, 34:36-43. (SCI, 1, IF: 8.201, 1 citation)

* Ai-Qun Yu, Nina Kurniasih Pratomo Juwono, Tee-Kheang Ng, Hua Ling, Han-Saem Cho, Susanna Su Jan Leong, Matthew Wook Chang. Genetic engineering of an unconventional yeast for renewable biofuel and biochemical production. Journal of Visualized Experiments, 2016, 115, e54371. (SCI, 4, IF: 1.113)

* Ai-Qun Yu, Nina Kurniasih Pratomo Juwono, Susanna Su Jan Leong, Matthew Wook Chang. Production of fatty acid-derived valuable chemicals in synthetic microbes. Frontiers in Bioengineering and Biotechnology, 2014, 2:78. (Will receive impact factor soon, 5 citations)

* Ai-Qun Yu, Jian-Chun Zhu, Biao Zhang, Lai-Jun Xing, Ming-Chun Li. Knockout of fatty acid desaturase genes in Pichia pastoris GS115 and its effect on the fatty acid biosynthesis and physiological consequences. Archives of Microbiology, 2012, 194(12):1023-1032. (SCI, 4, IF: 1.76, 2 citations)

* Ai-Qun Yu, Tong-Lei Shi, Biao Zhang, Lai-Jun Xing, Ming-Chun Li. Transcriptional regulation of desaturase genes in Pichia pastoris GS115. Lipids, 2012, 47(11):1099-1108. (SCI, IF: 1.892, 1 citation)

* Ai-Qun Yu, Tong-Lei Shi, Biao Zhang, Lai-Jun Xing, Ming-Chun Li. Effects of low temperature and exogenous unsaturated fatty acids on fatty acid desaturase gene expression of Mortierella alpina ATCC 16266. Acta Microbiologica Sinica, 2012, 52(11):1369-1377. (CA, BA, 1 citation)

* Ai-Qun Yu, Jian-Chun Zhu, Biao Zhang, Lai-Jun Xing, Ming-Chun Li. Effects of different carbon sources on the growth, fatty acids production, and expression of three desaturase genes of Mortierella alpina ATCC 16266. Current Microbiology, 2011, 62(5):1617-1622. (SCI, 4, IF: 1.519, 6 citations)

* Ai-Qun Yu, Xian-Zhang Jiang, Xiao-Feng Xia, Song-Gang Wu, Jian-Zhong Huang. Isolation and molecular identification of Mucor sp. EIM-10. Chinese Journal of Bioprocess Engineering, 2009, 7(2):74-78. (BIOSIS Previews, CA, 2 citations)

* Wei Suong Teo, Hua Ling, Ai-Qun Yu, Matthew Wook Chang. Metabolic engineering of Saccharomyces cerevisiae for production of fatty acid short- and branched-chain alkyl esters biodiesel. Biotechnology for Biofuels, 2015, 8:177. (SCI, 1, IF: 6.444)

* Tong-Lei Shi, Ai-Qun Yu, Ming Li, Meng Zhang, Lai-Jun Xing, Ming-Chun Li. Identification and characterization of a novel C20-elongase gene from the marine microalgae, Pavlova viridis, and its use for the reconstitution of two pathways of long-chain polyunsaturated fatty acids biosynthesis in Saccharomyces cerevisiae. Biotechnology Letters, 2013, 35(8): 1271-1282. (SCI, 3, IF: 1.639, 2 citations)

* Tong-Lei Shi, Ai-Qun Yu, Ming Li, Xiu-Yuan Ou, Lai-Jun Xing, Ming-Chun Li. Identification of a novel C22-Δ4-producing docosahexaenoic acid (DHA) specific polyunsaturated fatty acid desaturase gene from Isochrysis galbana and its expression in Saccharomyces cerevisiae. Biotechnology Letters, 2012, 34(12): 2265-2274. (SCI, 3, IF: 1.639, 5 citations)

* Jian-Zhong Huang, Xian-Zhang Jiang, Xiao-Feng Xia, Ai-Qun Yu, Ruo-Yu Mao, Xiao-Feng Chen, Bao-Yu Tian. Cloning and functional identification of delta5 fatty acid desaturase gene and its 5’-upstream region from marine fungus Thraustochytrium sp. FJN-10. Marine Biotechnology, 2011, 13(1):12-21. (SCI, 1, IF: 3.062, 7 citations)

* Hao Lan, Xiu-Yuan Ou, Ming Li, Ai-Qun Yu, Tong-Lei Shi, Lai-Jun Xing, Ming-Chun Li. Expression of Δ6-fatty acid elongase gene from Mortierella alpina in Pichia pastoris. Acta Scientiarum Naturalium Universitatis Nankaiensis, 2013, 46(2): 100-106. (CA)

专利申请:

* Matthew Wook Chang, Ai-Qun Yu, Nina Kurniasih Pratomo Juwono. Method of engineering microorganisms for the overproduction of short branched-chain fatty acids. Reference number: [US Provisional Patent Application No. 62/405,502].

科研项目                                                           

*天津科技大学“海河学者”培育计划引进人才基金;代谢工程改造解脂耶氏酵母生产生物化学品;2016-122019-11;项目主持人。

主讲课程                                                            

酿造酒工艺学(本科生),科技论文写作(研究生)

科研方向                                                            

所学专业为微生物学,主要从事酿酒酵母和非常规酵母代谢工程和合成生物学领域的研究工作,研究兴趣主要集中于:

 

[1] 利用代谢工程和合成生物学技术改造酿酒酵母和解脂耶氏酵母生产生物能源;

 

[2] 利用代谢工程和合成生物学技术改造酿酒酵母和解脂耶氏酵母生产大宗化学品;

 

[3] 利用代谢工程和合成生物学技术代谢工程改造酿酒酵母和解脂耶氏酵母生产精细化学品。

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