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副教授

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王洪彬,博士,天津科技大学生物工程学院教授,硕士生导师。天津微生物学会会员


主讲课程

本科生:微生物学实验

研究生:生物与医药仪器分析


科研领域及方向

[1] 酶工程, 以蛋白酶的表征改造生产和应用为主

[2] 肠道微生态与疾病和健康的关系。

[3] 系统生物学分析技术及其应用研究,以蛋白质组学和代谢组学为主


主要科研项目情况

[1] 国家重点研发计划“绿色生物制造”重点专项:医药与食品工业酶高效制备与催化技术创新,2021-2024.

[2] 国家自然科学基金面上项目:基于末端组学深度解析食品碱性蛋白酶的动态水解规律及其位点选择特性,2019-2022

[3] 国家重点研发计划项目,益生菌健康功能与基于肠道微生物组学的食品营养代谢机理研究,2017-2020

[4] 国家自然科学基金青年项目:可控酶解制备寡肽过程中肽谱变化规律的研究,2014-2016

[5] 国家重点研发计划项目:固体发酵工艺系统优化,2012-2015

[6] 国家自然科学基金国际(地区)合作与交流项目丝状真菌来源耐热脂肪酶的挖掘及其酶学特性的研究,2014-2017


主要学术成果

先后发表各类科研论文30篇,发明专利14项。近几年发表的主要学术论文有:

[1] Evaluation and verification of the characteristic peptides for detection of Staphylococcus aureus in food by targeted LC-MS/MS, Talanta, 2021: 122794.

[2] Insight into the cross-linking preferences and characteristics of the transglutaminase from Bacillus subtilis by in vitro RNA display, LWT2021151112152.

[3] Screening of the candidate inhibitory peptides of subtilisin by in vitro RNA display technique, International Journal of Biological Macromolecules, 2020, 163:1162-1167

[4] Evaluation of the site-unspecified peptide identification method for proteolytic peptide mapping. RSC Adv., 2020,10, 37182-37186.

[5] Characterization and application of a novel laccase derived from Bacillus amyloliquefaciens. International journal of biological macromolecules, 2020, 150:982-990

[6] Targeted Analysis of Candidate Characteristic Peptides of staphylococcus aureus[J]. Chin.J. Anal. Chem.,2020, 48(7) :921-927.

[7] A metabolomic explanation on beneficial effects of dietary Goji on intestine inflammation, Journal of Functional Foods, 2019, 53:109-114.

[8] A sensitive GC/MS detection method for analyzing microbial metabolites short chain fatty acids in fecal and serum samples, Talanta, 2019, 196:249-254.

[9] A comparative proteomics method for multiple samples based on a 18O-reference strategy and a quantitation and identification-decoupled strategy, Talanta, 2017, 171:166-172.

[10] A sample pretreatment method to suit the metabolomics analysis of Bacillus licheniformis based on GC-MS. Analytical Methods, 2017, 9, 2299-2304

[11] Electro-ultrafiltration to remove sodium dodecyl sulfate in proteins extracted for proteomics. RSC Advances, 2017, 7, 25144-25148

[12] Heat acclimation of Bifidobacterium longum and proteomic changes behind it. Probiotics and Antimicrobial Proteins, 2017, 9(3): 255-261.

授权发明专利主要有:

1.一种氢化可的松生物催化转化率的快速检测方法,ZL201511014228.7201

2.一种布氏乳杆菌发酵-转化-分离偶联制备甘露醇的方法,ZL201610851713.82019.


联系方式

办公地点:天津经济技术开发区第十三大街29号天津科技大学生物工程学院

邮政编码:300457


Emailwhb@tust.edu.cn