孟娇，博士，毕业于中国农业大学。天津科技大学生物工程学院讲师。中国科学院天津工业生物技术研究所博士后。

科研领域及方向

[1] 合成生物学与未来食品绿色制造

[2] 特色功能蛋白与多肽的微生物高效创制与性能改造

[3] 微生物环境应答机制与代谢调控解析

科研项目情况

[1] 中国博士后科学基金面上项目（2021M703439），Rcs 双组分系统对小肠结肠炎耶尔森菌胞膜压力的应答调控, 2021-2023，主持

[2] 十四五国家重点研发计划子课题（2023YFC3403604），木质素定向解聚合成儿茶酚等产物的底盘细胞的构建，2023-2028，主持

[3] 十四五国家重点研发计划（2021YFD1301002），一碳原料生物合成蛋白关键技术及新产品创制, 2021-2024，课题骨干

主要学术成果

先后发表各类科研论文23篇，授权发明专利6项。发表的主要学术论文有：

[1] Dong CC, Wu F, Liu SF, Rong YY, Hong K, Li YM, Meng J*, Wu X. Production of copper nanoparticles using genetically engineered Komagataella phaffii. Bioprocess and Biosystems Engineering, 2025, 48(9):1495-1508..

[2] Gao L , Meng J (co-first author) , Dai W ,et al. Deciphering cell wall sensors enabling the construction of robust P. pastoris for single-cell protein production. Biotechnology for Biofuels and Bioproducts, 2023, 16(1)

[3] Wu F, Ren FY, Xie XX*, Meng J*, Wu X. The implication of viability and pathogenicity by truncated lipopolysaccharide in Yersinia enterocolitica. Applied Microbiology and Biotechnology, 2023, 107(23):7165-7180

[4] Meng J, Liu SF, Gao L, Hong K, Liu SG, Wu X. Economical production of Pichia pastoris single cell protein from methanol at industrial pilot scale. Microbial Cell Factories, 2023, 22(1)

[5] Liu SF, Dong HF, Hong K, Meng J*, Lin LC*, Wu X. Improving methanol utilization by reducing alcohol oxidase activity and adding co-substrate of sodium citrate in Pichia pastoris. Journal of Fungi, 2023, 9(4)

[6] Meng J, Liu SF, Wu X. Engineered probiotics as live biotherapeutics for diagnosis and treatment of human diseases. Critical reviews in microbiology, 2023, 1-15

[7] Meng J, Glenn Y, Chen JY. The Rcs system in Enterobacteriaceae：envelope stress responses and virulence regulation. Frontiers in Microbiology, 2021

[8] Meng J, Huang C, Huang XN, Liu DY, Han BZ, Chen JY. Osmoregulated periplasmic glucans transmit external signals through Rcs phosphorelay pathway in Yersinia enterocolitica. Frontiers in Microbiology, 2020, 11: 122

[9] Meng J, Xu JH, Chen JY. Rcs phosphorelay responses to truncated lipopolysaccharide-induced cell envelope stress in Yersinia enterocolitica. Molecules, 2020, 25:23

[10] Meng J, Wang BY, Liu DY, Chen T, Wang ZW, Zhao XM. High-yield anaerobic succinate production by strategically regulating multiple metabolic pathways based on stoichiometric maximum in Escherichia coli. Microbial Cell Factories, 2016, 15: 141

授权发明专利主要有：

[1] 吴信,孟娇,刘书帆,高乐,鲍彤彤. 一种耐铜且高富集铜的毕赤酵母菌株及其应用. 专利号：2023103948058. 授权公告日2023-06-09

[2] 吴信,刘书帆,孟娇,刘曙光,鲍彤彤.一种耐高温且高甲醇转化率的毕赤酵母菌株及其应用.专利号：ZL 2023 1 0959715.9. 授权公告日2023-10-03

[3] 高乐,吴信,孟娇. 一种高甲醇耐受的毕赤酵母菌株的构建及其应用. 专利号：202211381199.8. 授权公告日2023-04-15

[4] 吴信,孟娇,高乐.一种高甲醇转化率且高蛋白的毕赤酵母菌株及其制备方法.专利号：ZL 202211146356.7. 授权公告日2022-12-09

[5] 陈晶瑜,孟娇,于波,张臻峰. 一个新的可用于合成肌肽的酶基因及其氨基酸序列. 专利号：ZL 201910428956.4. 授权公告日2020-12-01

[6] 陈晶瑜,孟娇. 一种二氢硫辛酰胺脱氢酶突变体蛋白及其制备方法和应用. 专利号：ZL 201710650938.1. 授权公告日2020-06-30

联系方式

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办公电话：022-6060xxxx

传 真：022-60602298

Email：jiaomeng@tust.edu.cn