天津科技大学生物工程学院欢迎您!
副教授

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宋亚囝 博士,天津科技大学生物工程学院副教授,工程生物学教研室主任,中国生物发酵产业协会淀粉糖分会、多元醇分会理事

主要研究方向:

· 微生物多糖代谢相关资源的功能研究与开发

· 益生菌及益生元的生理功能与应用研究

教育及科研经历:

· 2017.9-2018.9美国明尼苏达大学食品科学营养系访问学者

· 2013.7至今天津科技大学生物工程学院讲师、副教授

· 2011.5-2011.8德国汉堡工业大学生物过程与生物系统研究所访问学者

· 2006.9–2013.6中国科学院微生物研究所,微生物资源前期开发国家重点实验室,理学博士

· 2002.9–2006.6山东大学生命科学学院,生物工程专业,工学学士

承担科研任务

· 企业横向课题,饲用微生态制剂开发,山东泰山生力源集团,2021.11-2022.11,主持

· 天津科技发展战略研究计划,18JCZDJC33800,植物乳杆菌CGMCC8198HMG-CoA还原酶的转录调控及降血脂作用研究,2018.04-2021.03,参与

· 国家重点研发计划,2017YFD0400304,膳食功能因子与营养健康食品的靶向健康干预作用分析与评价,2017.07-2021.06子课题负责人

· 国家自然科学基金项目,31671842,液体发酵过程发菜多糖生物合成的调控机制研究,2017.01 -2020.12,参与

· 国家自然科学基金项目,31601409,大兴安岭多年冻土来源的低温木糖苷酶AX543冷适应机制的研究,2017.01-2019.12,参与

· 国家自然科学基金项目,31400031,寡糖转运在嗜碱芽孢杆菌 N16-5 半纤维素利用中的作用研究,2015.01-2017.12,主持

· 天津市科技计划项目,14JCZDJC33200L. caser HZ1新型降压肽的鉴定及其分子育种研究2014.01-2017.12,参与

发表论文

1. Yajian Song#*, Huitao Shen#, Tingting Liu, Bingju Pan, Sanduni De Alwis, Wanyi Zhang, Xuegang Luo, Zhongyuan Li, Nan Wang, Wenjian Ma, Tongcun Zhang*. Effects of Three Different Mannans on Obesity and Gut Microbiota of High-fat Diet-fed C57BL/6J Mice. Food & Function, 2021, 12(10):4606-4620

2. Wenting Liu#, Cuiping Ma#, Weidong Liu#, Yingying Zheng, Chun-Chi Chen, Ailing Liang, Xuegang Luo, Zhongyuan Li, Wenjian Ma, Yajian Song*, Rey-Ting Guo*, Tongcun Zhang*. Functional and structural investigation of a novel β-mannanase BaMan113A from Bacillus sp. N16-5. International Journal of Biological Macromolecules. 2021, 182: 899-909

3. 潘炳菊,张宛怡,申会涛,刘婷婷,李中媛,罗学刚,宋亚囝*.甘露寡糖分离纯化研究进展. 中国生物工程杂志. 2020, 40(11):90-95

4. 马翠萍,刘朵朵,潘炳菊,申会涛,宋亚囝*. 来源于嗜碱芽孢杆菌 N16-5甘露聚糖利用基因簇的乙酰酯酶 AesA的克隆及性质分析. 中国生物工程杂志. 2020, 40(3):65-71

5. Yajian Song#*, Wenyuan Sun#, Yanli Fan#, Yanfen Xue, Duoduo liu, Cuiping Ma, Wenting Liu, Wesley Mosher, Xuegang Luo, Zhongyuan Li, Wenjian Man, Tongcun Zhang*. Galactomannan Degrading Enzymes from the Mannan Utilization Gene Cluster of Alkaliphilic Bacillus sp. N165 and Their Synergy on Galactomannan Degradation. Journal of Agricultural and Food Chemistry. 2018, 66:11055-11063.

6. Yajian Song*, Duoduo Liu, Mengya Liu, Haixu Yang, Yanli Fan, Wenyuan Sun, Yanfen Xue, Tongcun Zhang, Yanhe Ma. Transcriptional Regulation of the Mannan Utilization Genes in the Alkaliphilic Bacillus sp. N16-5. FEMS Microbiology Letters. 2018, 365:fnx280

7. Yao Zhang, Yanli Fan, Haijie Hu, Haixu Yang, Xuegang Luo, Zhongyuan Li, Hao Zhou, Wenjian Ma, Yajian Song*, Tongcun Zhang. D-Tagatose Production by Lactococcus lactis NZ9000 Cells Harboring Lactobacillus plantarum L-Arabinose Isomerase. Indian Journal of Pharmaceutical Education and Research. 2017, 51:288-94

8. Wenyuan Sun, Yanli Fan, Jing Li, Gaoshaer Kayierhali, Xuejiao Liu, Yun Hao, Yirong Hou, Yajian Song*, Tongcun Zhang. Isolation and 16SrDNA Identification of Bacteria from Traditional Kazak Dairy Products. Advances in Applied Biotechnology. Lecture Notes in Electrical Engineering. 2017;444:803-9

9. Yajian Song, Jinshan Li, Shan Meng, Liang Yin, Yanfen Xue, Yanhe Ma*. A Novel Manno-Oligosaccharide Binding Protein Identified in Alkaliphilic Bacillus sp. N16-5 Is Involved in Mannan Utilization. PLoS One. 2016, 11:e0150059.

10. Wen Du, Yajian Song, Mengya Liu, Haixu Yang, Yao Zhang, Yanli Fan, Xuegang Luo, Zhongyuan Li, Nan Wang, Hongpeng He, Hao Zhou, Wenjian Ma, Tongcun Zhang*. Gene Expression Pattern Analysis of a Recombinant Escherichia coli Strain Possessing High Growth and Lycopene Production Capability when Using Fructose as Carbon Source. Biotechnology Letters. 2016, 38:1571-1577

11. Junzhen Bai#, Yanjian Song#, Xuegang Luo, Haixu Yang, Wen Du, Tongcun Zhang*. Construction of L-tert-Leucine producing strain by expressing heterologous leucine dehydrogenase and formate dehydrogenase in Escherichia coli. Advances in Applied Biotechnology. Lecture Notes in Electrical Engineering. 2015;333:21-30

12. Yajian Song, Yanfen Xue, Yanhe Ma*. Global Microarray Analysis of Carbohydrate Use in Alkaliphilic Hemicellulolytic Bacterium Bacillus sp. N16-5. PLoS One. 2013, 8:e54090


联系方式:022-60601104  songyajian@tust.edu.cn