仲飞亮，博士，天津科技大学生物工程学院讲师，硕士生导师。
主讲课程
本科生：《细胞生物学》、《基因编辑与合成基因组学》
研究生：《合成基因组学》
科研领域及方向
[1] 有益活性益生菌资源挖掘、功能机制研究及产业化应用
[2] 食品及农产品深加工
[3] 工程益生菌免疫治疗肿瘤
科研项目情况
[1] 重庆市技术创新与应用发展乡村振兴重点专项：重庆黔江脆红李益生菌发酵饮料开发、功能研究及产业化应用，2024-2026，项目负责人
[2] 中央引导地方科技发展资金——科技成果转移转化项目：有益活性微生物资源挖掘与产品研发，2024-2025，第一参与人
[3] 技术开发（委托）项目：益生菌/后生元成骨功效评价，2023-2024，项目负责人
[4] 技术开发（委托）项目：高产蛋白菌株的设计与构建，2023-2024，项目负责人
主要学术成果
以第一作者或通讯作者发表的学术论文有（†第一作者，*通讯作者）：
[1] Wen-Wen Zhao†, Yuan Gao, Yu-Ting Zhu, Fei-Liang Zhong*, Xue-Gang Luo*. SMYD3 plays a pivotal role in mediating the epithelial-mesenchymal transition process in breast cancer[J]. Biochemical and Biophysical Research Communications, 2025, 749,151363.
[2] 刘欣桐†,高园,李淼,高明英,仲飞亮*,罗学刚.基于群体感应工程菌免疫治疗肿瘤的研究进展.微生物学杂志, 2025.
[3] Xiaohong Wang†, Feiliang Zhong†, Tingting Chen†, Hongbo Wang, Weifang Wang, Hongkai Jin, Chouyang Li, Xuan Guo, Ying Liu, Yu Zhang*, Bo Li*. Cholesterol neutralized vemurafenib treatment by promoting melanoma stem-like cells via its metabolite 27-hydroxycholesterol[J]. Cellular and Molecular Life Sciences, 2024, 81(1): 226.
[4] Jia Liu†, Feiliang Zhong*, Yue Chen*. UCN-centric prognostic model for predicting overall survival and immune response in colorectal cancer[J]. Genes, 2024, 15, 1139.
[5] Feiliang Zhong†, Jia Liu, Chang Gao, Tingting Chen*, Bo Li*. Downstream regulatory network of MYBL2 mediating its oncogenic role in melanoma[J]. Frontiers in Oncology, 2022, 12: 816070.
[6] Feiliang Zhong†, Tingting Chen*, Bo Li*. Combinatorial transcriptional regulation of HEB/ZEB1/ASCL1 and MYBL2 on Ras/ErbB signaling[J]. Biochemical and Biophysical Research Communications, 2022, 622: 170-176.
[7] Jia Liu†, Feiliang Zhong†, Lei Cao, Ruiying Zhu, Junze Qu, Lin Yang, Tingting Chen, Yunlong Hu, Ying Wang, Mingdong Yao, Wenhai Xiao, Chun Li, Bo Li*, Yingjin Yuan. 7-dehydrocholesterol suppresses melanoma cell proliferation and invasion via Akt1/NF-κB signaling[J]. Oncology Letters, 2020, 20(6): 1-1.
[8] Fei-Liang Zhong†, Wei-Wei Dong, Songquan Wu, Jun Jiang, Deok-Chun Yang, Donghao Li, Lin-Hu Quan*. Biotransformation of gypenoside XVII to compound K by a recombinant β-glucosidase[J]. Biotechnology Letters, 2016, 38: 1187-1193.
[9] Fei-Liang Zhong†, Rui Ma, Mingliang Jiang, Wei-Wei Dong, Jun Jiang, Songquan Wu*, Donghao Li*, Lin-Hu Quan*. Cloning and characterization of ginsenoside-hydrolyzing β-glucosidase from Lactobacillus brevis that transforms ginsenosides Rb1 and F2 into ginsenoside Rd and compound K[J]. Journal of Microbiology and Biotechnology, 2016, 26(10): 1661-1667.
联系方式
办公地点：天津经济技术开发区第十三大街9号天津科技大学生物工程学院
邮政编码：300457
Email: flzhong91@tust.edu.cn
