天津科技大学生物工程学院欢迎您!
教授

于爱群,博士,天津科技大学生物工程学院教授,士生导师。天津市高层次人才计划入选者。天津科技大学海河学者培育计划人选。


主讲课程

本科生:酵母工艺学、酿酒技术概论

研究生:科技论文写作


科研领域及方向

[1]酵母代谢调控与分子育种

[2]利用进化工程、代谢工程、合成生物学及发酵工程手段改造酵母底盘合成高附加值工业产品

[3]现代酿造技术

[4]具有重要工业和医药应用价值的微生物菌种筛选与改良

[5]固体废弃物资源的微生物利用


科研项目情况

[1] 天津市自然科学基金绿色通道项目代谢工程改造解脂耶氏酵母生物合成功能性倍半萜化合物2018-2021

[2] 天津市教委科研计划项目重点项目代谢工程改造解脂耶氏酵母生物合成功能性单萜化合物2018-2021

[3] 天津科技大学海河学者培育计划引进人才基金代谢工程改造解脂耶氏酵母生产天然活性单萜2018-2022

[4] 天津市高层次人才计划基金代谢工程改造非常规酵母底盘生产高值化学品的研究,2018-2023


主要学术成果

先后发表各类科研论文35篇,申请发明专利5项。发表的主要学术论文有:

[1] Kun Zhu, Jing Kong, Baixiang Zhao, Lanxin Rong, Shiqi Liu, Zhihui Lu, Cuiying Zhang, Dongguang Xiao, Krithi Pushpanathan, Jee Loon Foo, Adison Wong, Aiqun Yu*. Metabolic engineering of microbes for monoterpenoid production. Biotechnology Advances, 2021. (IF: 14.227)

[2] Yu Zhao, Shiqi Liu, Zhihui Lu, Baixiang Zhao, Shuhui Wang, Cuiying Zhang, Dongguang Xiao, Jee Loon Foo, Aiqun Yu*. Hybrid promoter engineering strategies in Yarrowia lipolytica: isoamyl alcohol production as a test study. Biotechnology for Biofuels, 2021, 14: 149. (IF: 6.040)

[3] Jian Li, Kun Zhu, Lin Miao, Lanxin Rong, Yu Zhao, Shenglong Li, Lijuan Ma, Jianxun Li, Cuiying Zhang, Dongguang Xiao, Jee Loon Foo, Aiqun Yu*. Simultaneous improvement of limonene production and tolerance in Yarrowia lipolytica through tolerance engineering and evolutionary engineering. ACS Synthetic Biology, 2021, 10(4): 884-896. (IF: 5.110)

[4] Yakun Zhao, Kun Zhu, Jian Li, Yu Zhao, Shenglong Li, Cuiying Zhang, Dongguang Xiao, Aiqun Yu*. High-efficiency production of bisabolene from waste cooking oil by metabolically engineered Yarrowia lipolytica. Microbial Biotechnology, 2021, 0(0): 1-17. (IF: 5.813)

[5] 李建, 孔婧, 李圣龙, 赵禹, 赵雅坤, 肖冬光, 于爱群*. 适应性实验室进化技术在微生物育种中的应用进展. 生物工程学报, 2021, 37(1): 130-141.

[6] 孔婧, 朱坤,刘士琦, 荣兰新, 肖冬光, 于爱群*. 代谢工程改造解脂耶氏酵母合成植物萜类化合物的研究进展. 微生物学通报, 2021, 48(4): 1302-1313.

[7] 朱坤,孔婧, 荣兰新, 刘士琦, 肖冬光, 于爱群*. 代谢工程改造微生物合成单萜芳香产品的研究进展. 食品工业科技, 2021, 42(7): 390-398.

[8] Jian Li, Lanxin Rong, Yu Zhao, Shenglong Li, Cuiying Zhang, Dongguang Xiao, Jee Loon Foo, Aiqun Yu*. Next-generation metabolic engineering of non-conventional microbial cell factories for carboxylic acid platform chemicals. Biotechnology Advances, 2020, 43: 107605. (IF: 14.227)

[9] Aiqun Yu*, Yu Zhao, Jian Li, Shenglong Li, Yaru Pang, Yakun Zhao, Cuiying Zhang, Dongguang Xiao. Sustainable production of FAEE biodiesel using the oleaginous yeast Yarrowia lipolytica. MicrobiologyOpen, 2020, 9: e1051. (IF: 3.139)

[10] Yaru Pang, Yakun Zhao, Shenglong Li, Yu Zhao, Jian Li, Zhihui Hu, Cuiying Zhang, Dongguang Xiao, Aiqun Yu*. Engineering the oleaginous yeast Yarrowia lipolytica to produce limonene from waste cooking oil. Biotechnology for Biofuels, 2019, 12: 241. (IF: 6.040)

[11] Aiqun Yu*, Yakun Zhao, Yaru Pang, Zhihui Hu, Cuiying Zhang, Dongguang Xiao, Matthew Wook Chang, Susanna Su Jan Leong. An oleaginous yeast platform for renewable 1-butanol synthesis based on a heterologous CoA dependent pathway and an endogenous pathway. Microbial Cell Factories, 2018, 17: 166. (IF: 5.328)

[12] Aiqun Yu, Nina Kurniasih Pratomo Juwono, Jee Loon Foo, Susanna Su Jan Leong, Matthew Wook Chang*. Metabolic engineering of Saccharomyces cerevisiae for the overproduction of short branched-chain fatty acids. Metabolic Engineering, 2016, 34: 36-43. (IF: 9.783)

[13] Aiqun Yu, Nina Kurniasih Pratomo Juwono, Susanna Su Jan Leong, Matthew Wook Chang*. Production of fatty acid-derived valuable chemicals in synthetic microbes. Frontiers in Bioengineering and Biotechnology, 2014, 2: 78. (IF: 5.890)

申请发明专利主要有:

[1] Matthew Wook Chang, Aiqun Yu, Nina Kurniasih Pratomo Juwono. Method of engineering microorganisms for the overproduction of short branched-chain fatty acids. Reference number: [US Provisional Patent Application No. 62/405,502], 2016-10-07.

[2] Matthew Wook Chang, Aiqun Yu, Nina Kurniasih Pratomo Juwono. Development of a novel yeast platform for 1-butanol synthesis. Reference number: [US Provisional Patent Application No. 62/432,472], 2016-11-17.

[3] 于爱群, 庞亚如, 赵雅坤, 张翠英, 肖冬光. 一株产柠檬烯的解脂耶氏酵母及其构建方法与应用 申请号:201810441360.3),2018-05-10.

[4] 于爱群,李建,赵禹,肖冬光. 一种生产柠檬烯的解脂耶氏酵母工程菌(申请号:201910948468.6),2019-10-08.

[5] 于爱群,赵雅坤,李建,李圣龙,赵禹,朱坤,张翠英,肖冬光. 一种产红没药烯的解脂耶氏酵母及其构建方法与用途(申请号:201911169971.8),2019-11-26.


联系方式

办公地点:天津经济技术开发区第十三大街29号天津科技大学生物工程学院

邮政编码:300457

办公电话:022-60602723

真:022-60602298


Emailyuaiqun@tust.edu.cn